Dr. Greg Bowman is the Louis Heyman University Professor at the University of Pennsylvania.

He has served as the director of Folding@home since 2018.

Greg and his lab devise new ways to design therapeutics and interpret genetic variation in areas ranging from viral infections like Ebola to Alzheimer’s and cardiac disease. A major emphasis is on identifying cryptic pockets (pockets that are absent in single snapshots of what a protein typically looks like but form due to protein dynamics) and allostery by mapping out the ensemble of different structures that a protein adopts. To build and exploit these maps, the group combines biophysical experiments, physics-based simulations, and machine learning.

Greg was inspired to pursue a career in biomedical research after losing much of his vision to a juvenile form of macular degeneration.

You can learn more about Greg and his lab’s research trajectory, which started at Washington University before moving to U Penn, from the movie below.